If you have a laptop from Lenovo and it has the Lenovo Vantage app installed, check all your systems/updates. It should be an app. There should be a section to click on device settings > input > scroll to FnLock and turn it on.
I've been having the same issues where my Esc, Tab and 1 have completely stopped working, and I'm not too sure what to do, so I'm forced to hold down the Fn button to decrease/increase the sound and brightness. Figuring this out helped me a ton without having to hold down the Fn button, as the Fn stays locked now.